GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THCA | cis | rs950169 | 1 | rs62026530 | chr15:84775840 | LOC388152 | chr15:84867600-84898920:- | -0.71 | -12.88 | 8.25E-33 | Schizophrenia |
| THCA | cis | rs950169 | 1 | rs62026530 | chr15:84775840 | NMB | chr15:85198362-85201802:- | 0.23 | 4.68 | 3.7E-6 | Schizophrenia |
| THCA | cis | rs950169 | 1 | rs62026530 | chr15:84775840 | SH3GL3 | chr15:84116091-84287491:+ | 0.24 | 3.76 | 0.000193 | Schizophrenia |
| THCA | cis | rs3743772 | 1 | rs62048488 | chr16:53453939 | AKTIP | chr16:53525193-53537170:- | -0.39 | -5.24 | 2.45E-7 | Depressive symptoms (SSRI exposure interaction) |
| THCA | cis | rs62055045 | 1 | rs62055045 | chr16:71396661 | CALB2 | chr16:71392626-71424339:+ | 0.43 | 5.34 | 1.4E-7 | Schizophrenia |
| THCA | cis | rs62055045 | 1 | rs62055045 | chr16:71396661 | HPR | chr16:72097125-72111144:+ | -0.31 | -3.89 | 0.000114 | Schizophrenia |
| THCA | cis | rs62055045 | 1 | rs62055047 | chr16:71401027 | CALB2 | chr16:71392626-71424339:+ | 0.45 | 5.54 | 5.03E-8 | Schizophrenia |
| THCA | cis | rs62055045 | 1 | rs62055047 | chr16:71401027 | HPR | chr16:72097125-72111144:+ | -0.33 | -4.11 | 4.58E-5 | Schizophrenia |
| THCA | cis | rs34286592 | 1 | rs62056375 | chr16:29857901 | MAPK3 | chr16:30125427-30134630:- | -0.24 | -3.38 | 0.000779 | Multiple sclerosis |
| THCA | cis | rs11079321 | 1 | rs62058157 | chr17:55745687 | BZRAP1 | chr17:56378596-56406152:- | 0.18 | 4.22 | 2.95E-5 | Coronary artery calcification |
| THCA | cis | rs9902453 | 1 | rs62070270 | chr17:28263980 | ANKRD13B | chr17:27916801-27941778:+ | 0.36 | 8.96 | 7.45E-18 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070270 | chr17:28263980 | CORO6 | chr17:27941774-27948441:- | 0.51 | 11.99 | 3.97E-29 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070270 | chr17:28263980 | EFCAB5 | chr17:28256874-28435469:+ | 0.58 | 11.15 | 8.21E-26 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070270 | chr17:28263980 | GIT1 | chr17:27900487-27916610:- | 0.31 | 7.43 | 4.88E-13 | Coffee consumption (cups per day) |
| THCA | cis | rs9902453 | 1 | rs62070270 | chr17:28263980 | LRRC37B2 | chr17:28903483-28992715:+ | 0.19 | 4.18 | 3.42E-5 | Coffee consumption (cups per day) |